| First Author | Levy JE | Year | 1998 |
| Journal | MGI Direct Data Submission | Mgi Jnum | J:46866 |
| Mgi Id | MGI:1202171 | Citation | Levy JE, et al. (1998) The Transferrin Receptor (Trfr) maps to mouse Chromosome 16. MGI Direct Data Submission |
| abstractText | The human homolog of Trfr has been mapped to 3q26. Its location is on the same band as transferrin, whose murine homolog maps to chromosome 9. The human 3q26 region shares synteny with both mouse chromosomes 9 and 16. Our data suggest that the breakpoint of homology between the human genomic region 3q and mouse chromosomes 9 and 16 is located between Trf and Trfr. This is interesting in light of the ligand, receptor interaction of these two genes. Several genes involved in iron metabolism have recently been cloned and localized in the mouse, including Hfe and Nramp2. The localization of Trfr, a key gene in iron metabolism is an important addition to the field. |
