| First Author | Agulnik SI | Year | 1989 |
| Journal | Mouse News Lett | Volume | 84 |
| Pages | 108-9 | Mgi Jnum | J:14261 |
| Mgi Id | MGI:62433 | Citation | Agulnik SI, et al. (1989) Localization of insertions Is(HSR;1C5)1Icg and Is(HSR;1D)2Icg on the genetic map. Mouse News Lett 84:108-9 |
| abstractText | Full text of MNL contribution: To localize insertions Is(HSR;1C5)1Icg and Is(HSR;1D)2Icg on the genetic map, matings have been conducted of females heterozygous for a block of insertions, which was isolated from the Jakutsk (Northeast Siberia) population (MNL, 78, 70). The data (Table 1) show a close linkage of the block of insertions and leaden locus (RF=o.71+0.01). Table 1. Genotype (female/female) Ð fzln++/++Is1Is2 Genotype (male/male) Ð fzln++/fzln++ Total: 140 Offspring phenotype: ++Is1Is2: 51 fzln++: 20 fz+Is1Is2: 37 +ln++: 31 fzlnIs1Is2: 0 ++++: 1 There was no crossing-over found between the two insertions. The similar data were obtained from the analysis of the offspring of females heterozygous for a block of insertions from the Novosibirsk population (Table 2). In this case there were no recombinants between ln and Is1Is2. Table 2. Genotype female female: ln++/+Is1Is2 Genotype male/male: ln++/ln++ Total: 75 Offspring phenotype: +Is1Is2: 53 ln++: 22 lnIs1Is2: 0 +++: 0 It was impossible to establish the order of ln locus and Is1 Is2 on the genetic map due to their close linkage in these experiments. In both cases the number of offsprings with abnormal Chr. 1 is larger than that of offsprings with normal Chr. 1, which is connected with a meiotic drive for Chr. 1 with insertions (MNL, 81, 78-79; Genetika (USSR) in press). |
