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Publication : Activation of NF-?B in Schwann cells is dispensable for myelination in vivo.

First Author  Morton PD Year  2013
Journal  J Neurosci Volume  33
Issue  24 Pages  9932-6
PubMed ID  23761888 Mgi Jnum  J:199167
Mgi Id  MGI:5500975 Doi  10.1523/JNEUROSCI.2483-12.2013
Citation  Morton PD, et al. (2013) Activation of NF-kappaB in Schwann cells is dispensable for myelination in vivo. J Neurosci 33(24):9932-6
abstractText  Peripheral myelination is a dynamic process orchestrated by axons and Schwann cells. Although the signaling mechanisms governing myelination are not fully understood, NF-kappaB activation in Schwann cells has been implicated as a key regulator in vitro. Using a mouse model, we show that nuclear factor kappaB activation in Schwann cells is not required for myelination in vivo.
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