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HT Experiment :

Experiment Id  E-CBIL-6 Name  Transcription profiling of HNF4 alpha null mice to investigate the phenotype of dis-regulated insulin secretion and abnormal beta cell growth
Experiment Type  transcription profiling by array Study Type  WT vs. Mutant
Source  ArrayExpress Curation Date  2019-04-09
description  The aim of this experiment was to use microarray analysis to examine the phenotype of dis-regulated insulin secretion and abnormal beta cell growth in HNF4 alpha null mice. These mice show impaired glucose tolerance and elevated fasting and fed plasma insulin levels. Rana Gupta from Klaus Kaestner's Lab extracted RNA from isolated islets. Three controls and five mutants were provided for the study.
  • variables:
  • genotype

1 Publications

Trail: HTExperiment

8 Samples

Trail: HTExperiment