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HT Experiment :

Experiment Id  E-GEOD-45583 Series Id  GSE45583
Name  A hypomorphic Lsd1 allele results in heart development defects in mice Experiment Type  transcription profiling by array
Study Type  WT vs. Mutant Source  ArrayExpress
Curation Date  2019-02-06
description  Microarray characterization of Lsd1 knock-outs compared to littermate controls Microarrays were employed to identify transcripts that were differentially modulated in the hearts of wild-type and Lsd1-hypomorphic late-stage embryos. Late-stage embryonic hearts were isolated from wild-type and Lsd1-hypomorphic hearts, in order to isolate RNA for hybridization on Affymetrix microarrays. We sought to identify gene products that are differentially regulated between the two genotypes, in order to explain the observed ventricular septal defects in the hypomorphic animals.
  • variables:
  • genotype

0 Publications

8 Samples

Trail: HTExperiment