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HT Experiment :

Experiment Id  E-GEOD-77813 Series Id  GSE77813
Name  Genome-wide analysis of epidermal gene expression from Presenilin (1&2)-null, RBPjk-null and wild-type litter mates Experiment Type  transcription profiling by array
Study Type  WT vs. Mutant Source  ArrayExpress
Curation Date  2019-05-31
description  Analysis of differential gene expression in Psen-null and RBPjk-null epidermal keratinocytes. The hypothesis tested in the present study was that canonical Notch signals could be present at the beginning of epidermal stratification (E13.5) in the RBPj-null epidermis. If an early signal was preserved by epigenetic memory, E18.5 RBPj-null epidermis would resemble the wild-type at the transcriptional level. Total RNA obtained from 3xRBPj-null and 3xPsen-null epidermis at E18.5 and compared to wild-type (3xRBPjwt & 3xPsenwt) epidermis from littermates.
  • variables:
  • genotype

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment