Experiment Id | E-MEXP-582 | Name | Transcription profiling by array of CREM-knockout mice |
Experiment Type | transcription profiling by array | Study Type | WT vs. Mutant |
Source | ArrayExpress | Curation Date | 2019-03-14 |
description | To assess a potential role of transcription factor CREM in the long-term detrimental effects of beta1-adrenoceptor overexpression, four mouse lines were generated and studied: wild-type mice (WT), Crem-normal beta1AR-transgenic mice (beta1ARTG), Crem-deficient non-transgenic mice (Crem-/-) and Crem-deficient beta1AR-transgenic mice (beta1ARTG/Crem-/-). We focused on genes up- or down-regulated in transgenic mice due to the lacking of CREM (beta1ARTG/Crem-/- vs. beta1ARTG). |