| Experiment Id | E-GEOD-13227 | Series Id | GSE13227 |
| Name | Transcription profiling of mouse thymus from AKR/J x FVB/NJ F1 versus DBA/2J x FVBF1 reveals 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms | Experiment Type | transcription profiling by array |
| Study Type | Baseline | Source | ArrayExpress |
| Curation Date | 2018-04-19 |
| description | F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from normal tissues Experiment Overall Design: Thymus from adult F1 animals from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes |
