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HT Experiment :

Experiment Id  E-GEOD-39769 Series Id  GSE39769
Name  Development of gene expression signatures in testis for plin1-null mice Experiment Type  transcription profiling by array
Study Type  WT vs. Mutant Source  ArrayExpress
Curation Date  2019-05-28
description  We have employed whole genome microarray expression profiling as a discovery platform to identify the effect of plin1 on gene expression during testis development. Testis of day 21, day 40, and day 60 in plin1-null mice and wild type mice were analyzed. Expression of a list genes (including cyp51, prm1, tnp2) from this signature was quantified in the same RNA samples by real-time PCR, confirming the influence of plin1 on testis development. plin1 knockout alteration gene expression in mice testis was measured at different development phases: day 21 meiosis phase, day 40 puberty phase, and day 60 mature phase. There independent experiments were performed at each time (d21, d40, d60).
  • variables:
  • genotype,
  • age

1 Publications

Trail: HTExperiment

18 Samples

Trail: HTExperiment