Experiment Id | E-MTAB-921 | Name | Transcription profiling of mouse E10.5 female embryos wild-type and mutant for Smchd1 |
Experiment Type | transcription profiling by array | Study Type | WT vs. Mutant |
Source | ArrayExpress | Curation Date | 2017-06-14 |
description | To investigate the role of the Smchd1 protein in epigenetic silencing of autosomal loci, we carried out a comparative microarray gene expression analysis of wild-type and Smchd1-/- female embryos at E10.5. Embryos were collected at E10.5 after natural mating, sexed and genotyped. Total RNAs were extracted from three individual wild-type and three Smchd1-/- female embryos and cRNAs prepared from these samples was hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 array. |