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HT Experiment :

Experiment Id  E-GEOD-30314 Series Id  GSE30314
Name  Expression data from mouse heart with and without GATA4 S105A mutation; with and without adrenergic stress Experiment Type  transcription profiling by array
Study Type  WT vs. Mutant Source  ArrayExpress
Curation Date  2019-01-15
description  Serine 105 phosphorylation of GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. We used microarrays to detail global gene expression program alterations that arise in response to the ablation of the Gata4 S105 phosphorylation site in basal and adrenergic-stressed heart ventricles. Wildtype and genetically engineered mice were subjected to control or pseudoephedrine treatment and heart ventricle RNAs were extracted and hybridized on Affymetrix microarrays. Comparisons consisted of identifying treatment- and genotype-affected gene expression patterns.
  • variables:
  • genotype

1 Publications

Trail: HTExperiment

8 Samples

Trail: HTExperiment