| Experiment Id | E-MEXP-2570 | Name | Transcription profiling of mice wild-type and pcd3J-/- to investigate abnormal sperm development in pcd3J |
| Experiment Type | transcription profiling by array | Study Type | WT vs. Mutant |
| Source | ArrayExpress | Curation Date | 2018-08-07 |
| description | Findings from gene expression studies can help identify relevant biological pathways. RNA from three pairs of testes from wild-type and pcd3J-/- mice at postnatal day 18 was subjected to a genome-scale gene expression analysis using the Affymetrix GeneChip Mouse Gene 1.0 ST Array, which includes approximately 28,000 genes. RNA from postnatal day 18 was used to minimize the changes in gene expression that might occur in response to pathological changes in the pcd3J-/- mice, because postnatal day 18 was the earliest time point at which structural differences between testes from wild-type and pcd3J-/- mice were observed via histopathology.Three pcd3J-/- mutant mice and three corresponding wild-type (pcd3J+/+) littermates at postnatal day 18 were used for the microarray analyses. |
