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HT Experiment :

Experiment Id  E-MTAB-3517 Name  The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing
Experiment Type  transcription profiling by array Study Type  WT vs. Mutant
Source  ArrayExpress Curation Date  2018-11-02
description  The Moonwalker (Mwk) mouse is a model of dominantly inherited cerebellar ataxia caused by a gain-of-function mutation in the transient receptor potential (TRP) channel TRPC3. We report impairments in dendritic growth and synapse formation early on during Purkinje cell development in the Mwk cerebellum that are accompanied by alterations in calcium signaling.
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1 Publications

Trail: HTExperiment

8 Samples

Trail: HTExperiment




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