| Experiment Id | E-GEOD-60375 | Series Id | GSE60375 |
| Name | Role of Capicua in metabolic system | Experiment Type | transcription profiling by array |
| Study Type | WT vs. Mutant | Source | ArrayExpress |
| Curation Date | 2019-03-20 |
| description | CIC is a HMG box-containing transcriptional repressor evolutionarily conserved from C. elegans to human. It's known to associate with various types of cancer but physiological function of CIC remain largely unknown. In this study, we characterized Cic hypomorphic (Cic-L-/-) mice and identified critical roles for of CIC in drug metabolism and bile acid homeostasis. Total RNA obtained from isolated liver tissue of Cic-L-/- mouse compared to liver tissue of normal mouse |
