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HT Experiment :

Experiment Id  E-GEOD-39585 Series Id  GSE39585
Name  Decrease of Parkin and CD36 expression and body weight correlate with an increase of non-esterified fatty acids in a mouse model for TDP-43 pathology Experiment Type  transcription profiling by array
Study Type  WT vs. Mutant Source  ArrayExpress
Curation Date  2019-01-09
description  TDP-43-coding mutations are found among ALS patients. In order to express human mutant TDP-43 protein in the mouse under the control of the endogenous Tardp promoter, we have generated a mouse line with 300% elevated TDP-43 level. Total RNA obtained from 4-6 male mutant mice was compared to 4-6 wild type controls.
  • variables:
  • genotype,
  • anatomical structure

1 Publications

Trail: HTExperiment

20 Samples

Trail: HTExperiment