Experiment Id | E-GEOD-39585 | Series Id | GSE39585 |
Name | Decrease of Parkin and CD36 expression and body weight correlate with an increase of non-esterified fatty acids in a mouse model for TDP-43 pathology | Experiment Type | transcription profiling by array |
Study Type | WT vs. Mutant | Source | ArrayExpress |
Curation Date | 2019-01-09 |
description | TDP-43-coding mutations are found among ALS patients. In order to express human mutant TDP-43 protein in the mouse under the control of the endogenous Tardp promoter, we have generated a mouse line with 300% elevated TDP-43 level. Total RNA obtained from 4-6 male mutant mice was compared to 4-6 wild type controls. |