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HT Experiment :

Experiment Id  E-MTAB-6132 Name  miRNAseq analysis of Chrnb4-cre driven Dicer conditional knockout (Dicer CKO) whole retinas
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  ArrayExpress Curation Date  2019-03-06
description  We have shown that Chrnb4-cre; Dicerflox/flox retinas (Dicer CKO) display a cone dystrophy by postnatal day P21, independent of rod degeneration. To elucidate which miRNAs were involved in such phenotype, miRNA sequencing was performed in whole retinas of P21 and 3.5 month old control and Dicer CKO mice. This experiment aims to identify which miRNAs were differentially expressed in Dicer conditional knockout mice when compared to control mice.
  • variables:
  • bulk RNA-seq,
  • genotype,
  • age

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment