|  Help  |  About  |  Contact Us

HT Experiment :

Experiment Id  GSE128361 Name  Hepatic transcriptomics reveals that lipogenesis is a key signaling pathway in isocitrate dehydrogenase 2 deficient mice
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2022-07-13
description  The present study was conducted to capture signatures of isocitrate dehydrogenase 2 deficient (Idh2-/-) mice liver transcriptome using mRNA sequencing technique which provides information to discover new transcripts and to quantify transcript levels. Using this mRNA sequencing results, bioinformatic analyses will be performed to further identify key biological functions of Idh2 influencing disease-related signaling pathways. Hepatic mRNA profiles of wild type (WT) and Idh2-/- mice were generated by deep sequencing, in triplicate, using Illumina HiSeq 2500.
  • variables:
  • bulk RNA-seq,
  • sex,
  • genotype

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment