Experiment Id | GSE87032 | Name | Early-life stress of Cntnap2 heterozygous mice demonstrates a gene by environment interaction model for developmental brain disorders |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2022-09-19 |
description | We examined whether adult heterozygous mice (Cntnap2+/-; phenotypically normal) subjected to an early-life stress would have social-related deficits and disruptions in 5-hydroxymethylcytosine (5hmC), similar to the Cntnap2-/-. Profiled genome-wide 5hmC and RNA expression in the striatum of prenatal stressed and non-stressed mice that were wild type or heterozygous for the Cntnap2 gene |