| Experiment Id | GSE127976 | Name | Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2022-12-13 |
| description | Purpose: The goals of this study are to compare the LGE-derived cells changes gene expression profiles between controls and Zfhx3 conditional knockout mice Methods: Total RNA was isolated and sequenced using an illumina high-seq 2500. Raw data was analyzed using TopHat. Genes were considered significantly changed whicn perform P value <= 0.05 Results: Compared to controls, 1620 genes were significantly down regulated, and 2108 genes were up regulated in the RNA expression level of the mutant LGE. LGE RNA profiles of E16.5 control mouse brain and Zfhx3 conditional knockout mouse brain |
