Experiment Id | GSE92539 | Name | The histone code reader Spin1 controls skeletal muscle development |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2022-11-18 |
description | We report developmental defects in Spin1(Myf5-Cre) mice, in which Spin1 is ablated in skeletal muscle. RNA sequencing of skeletal muscle of Spin1(Myf5-Cre) and control fetuses at E15.5 and E16.5 and of tibialis anterior of surviving Spin1(Myf5-Cre) and control mice at three weeks of age (P21). ChIP sequencing using primary myoblast isolated from 10-day old mice and anti-SPIN1 antibody (custom SPIN1-5867) or anti-H3K4me antibody (Diagenode, C15410003). |