Experiment Id | GSE64440 | Name | Gene expression profiling of E15.5 FoxD1 Cre;Dicer and control embryonic kidneys |
Experiment Type | transcription profiling by array | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2022-10-31 |
description | The aim of this study is to address the functional role of miRNAs in the FoxD1+ renal stroma progenitors and derivatives during embryonic kidney development. To achieve this, we generated transgenic mice that lack miRNAs in the renal stroma lineage (FoxD1 Cre;Dicer), and performed a microarray analysis on E15.5 whole kidneys to determine the transcriptional changes. 3 litters of E15.5 FoxD1 Cre;Dicer and control littermate kidneys were used for the microarray analysis. Each litter consists of kidneys pooled from 2 embryos per genotype for the RNA extraction. |