| Experiment Id | GSE121214 | Name | Transcription Factors Dlx1/2 Are Required for Making All Interneurons in the Olfactory Bulb [Dlx1/2] |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2022-11-18 |
| description | Purpose: To assess changes in gene expression profiles from the E16.5 wild type littermate controls LGE and Dlx1/2-/- mutant mice LGE (lateral ganglionic eminence). Methods: Total RNA was isolated and sequenced using an Illumina Hi-seq 2500. Raw data was analyzed using TopHat. Genes were considered significantly changed which perform fold-change>=2 and P value <= 0.05. Results: Compared to controls, 804 genes were significantly down regulated, and 673 genes were up regulated in the RNA expression level of the mutant LGE. LGE RNA profiles of E16.5 Wild type mouse brain and Dlx1/2-/- mutant mouse brain. |
