| Experiment Id | GSE249433 | Name | Single-nucleus transcriptomic highlights sex differences in cardiac molecular signaling and identifies a novel cardiomyocyte population associated with CCNA2-mediated cardiac regeneration |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | GEO | Curation Date | 2025-01-22 |
| description | Adult mammalian hearts lack regenerative potential and this is a significant contributing cause of the extensive morbidity and mortality of cardiovascular disease. We performed single nucleus RNA sequencing (snRNA-seq) to capture of cell diversity and gender-specific changes as well as identification of critical differentially expressed genes in cellular clusters throughout the heart. Adult hearts isolated from female and male normal wild-type (both nontransgenic-nTG and CCNA2 constitutively expressing-Transgenic-Tg) mice. |
| notes | bioRxiv preprint: https://doi.org/10.1101/2024.03.01.583057 |
