| Experiment Id | GSE139824 | Name | Mouse_Tbx5_del_CreERT2_bulk_RNAseq |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-02-13 |
| description | Haploinsufficiency of transcriptional regulators causes human congenital heart disease (CHD), suggesting that reduced transcription factor dosage causes a gene regulation imbalance. Here, we define transcriptional responses to reduced TBX5 in embryonic mouse hearts. Embryonic heart mRNA profiles at E10.5 of wildtype (WT), Tbx5 CreERT2/+, Tbx5 del/+ and Tbx5 del/CreERT2 were generated by deep sequencing, in quadruplicate. |
