| Experiment Id | GSE157983 | Name | Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2024-11-06 |
| description | We studied conditional knockout mice in which the vast majority of dentate granule cells (DGCs) fail to develop--including nearly all DGCs in the dorsal hippocampus--secondary to eliminating Wntless (Wls) in a subset of cortical progenitors with Gfap-Cre. Bulk RNA-seq and single nuclei RNA-seq were preformed on hippocampi from adult control, Gfap-Cre;Wlsfl/+, and mutant, Gfap-cre;Wlsfl/- mice. |
