Experiment Id | GSE205624 | Name | Effects of Conditional Egfr deletion on transcriptome of the mouse cerebral cortex |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-03-14 |
description | To investigate the role of Egfr in the cerebral cortex and hippocampal formation we conditionally deleted it using a floxed allele in combination with the Nestin-cre transgene. Cortices at E17.5 embryonic stage were harvested and split into rostral and caudal halves and RNA extracted and sequenced Comparison of RNA-seq data between rostral and caudal cortices and hippocampal formation of control brains (EgfrF/+ genotype) and brain-specific knock of Egfr (Nestin-EgfrF/F). |