Experiment Id | GSE228812 | Name | PD-1-PD-L1 Axis Activation Suppresses CD8+ T Cells and Improves Nephritis [scRNA-seq, scTCR-seq] |
Experiment Type | RNA-Seq | Study Type | Baseline |
Source | GEO | Curation Date | 2025-01-30 |
description | To dissect whether PD-1+CD8+ T cells are exhausted in lupus nephritis, scRNA-seq were performed to define the heterogeneous and pathologic subset. Splenic and kidney-infiltrating PD-1+CD8+ T cells were sorted for scRNA and scTCR sequencing. |