| Experiment Id | GSE83243 | Name | Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-08-09 |
| description | We isolated RNAs from Otp-lineage cells in the mouse brain using translating ribosome affinity purification (TRAP) approach. We compared two groups of mice: Otp-cre; ROSAfsTRAP (control) and Otp-cre; Cicf/f; ROSAfsTRAP (conditional knockout). Following RNA isolation, RNAseq was performed and gene expression profiles were compared between controls and conditional knockouts. Examination of gene expression in Otp-lineage neurons in two mouse groups. |