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HT Experiment :

Experiment Id  GSE83243 Name  Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2023-08-09
description  We isolated RNAs from Otp-lineage cells in the mouse brain using translating ribosome affinity purification (TRAP) approach. We compared two groups of mice: Otp-cre; ROSAfsTRAP (control) and Otp-cre; Cicf/f; ROSAfsTRAP (conditional knockout). Following RNA isolation, RNAseq was performed and gene expression profiles were compared between controls and conditional knockouts. Examination of gene expression in Otp-lineage neurons in two mouse groups.
  • variables:
  • genotype,
  • bulk RNA-seq

1 Publications

Trail: HTExperiment

8 Samples

Trail: HTExperiment