Experiment Id | GSE45358 | Series Id | E-GEOD-45358 |
Name | Gene expression analysis of murine peritoneal macrophages deficient for SAMHD1 and IFNAR | Experiment Type | RNA-Seq |
Study Type | WT vs. Mutant | Source | GEO |
Curation Date | 2023-08-08 |
description | To investigate the contribution of type-1 IFN signalling to the upregulation of IFN- stimulated genes in SAMHD1-deficient cells, we performed global gene expression analysis of SAMHD1-deficient IFNAR-/- macrophages. Peritoneal macrophages from ten SAMHD1-deficient IFNAR-/- and six SAMHD1-deficient controls were FACS sorted. RNA was subjected to next generation mRNA sequencing. |