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HT Experiment :

Experiment Id  GSE50739 Series Id  E-GEOD-50739
Name  Tgif1 regulates quiescence and self-renewal signaling pathways of hematopoietic stem cells (HSCs) Experiment Type  RNA-Seq
Study Type  WT vs. Mutant Source  GEO
Curation Date  2023-08-08
description  In this study we demonstrate that Tgif1 has a role in HSCs maintenance, self-renewal and quiescence. RNA sequencing data of LSK cells (HSCs enriched cell population) from Tgif1-/- and wild type mice implicates that multiple pathways involved in HSC quiescence and self-renewal are disturbed in Tgif1 deficient mice. RNA expression profiles of wild type (WT) and Tgif1-/- LSK cells were generated by RNA sequencing, in triplicate, using Illumina HiSeq 2000.
  • variables:
  • genotype,
  • bulk RNA-seq

1 Publications

Trail: HTExperiment

6 Samples

Trail: HTExperiment