Experiment Id | GSE69276 | Series Id | E-GEOD-69276 |
Name | Notch1 dose modulates endothelial gene expression | Experiment Type | RNA-Seq |
Study Type | WT vs. Mutant | Source | GEO |
Curation Date | 2024-07-10 |
description | Purpose: To use RNA-Seq analysis of endothelial cell in various Notch1 alllels in order to determine transcrptional differences as a consequence of Notch dose. Methods: Using a FACS sorting we generated high-throughput RNA-SEQ data of endothelials in various Notch1 alleles during development Results: Notch1 dose can alter gene expression in a subset of endothelial genes RNA-Seq was performed on endothelial cells isolated at e9.5 from embryos with various Notch1 alleles including N1+/+, N1+/-, N1+/vg, N112/vg, N112/- |