Experiment Id | GSE189304 | Name | Effects of TMEM216 on the transcriptomes of E12 mice embryos |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2025-01-06 |
description | RNA-seq analysis of tissues from E12 Tmem216+/+ and Tmem216-/- embryos were performed to identify the mechanism underlying TMEM216 affecting ciliogenesis. After quantified by TBS380, paired-end RNA-seq sequencing library was sequenced with the Illumina HiSeq xten. Our results demonstrate that TMEM216 deficiency impairs Hh signaling pathway of mice. mRNA profiles of E12 Tmem216+/+ and Tmem216-/- embryos |