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HT Experiment :

Experiment Id  GSE137945 Name  Next Generation Sequencing of PKD2 mutant mice
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2023-10-19
description  Purpose: Determine the differential gene expression pattern between wildtype, Pkd2-KO and Pkd2-miR-214 KO mice Methods: kidney mRNA profiles of Pkd2-KO and Pkd2-mir-214-KO mice was sequenced with N of 3 in each group Results: 972 differentially expressed transcripts were identified between Pkd2-KO kidneys and Pkd2-miR-214-KO kidneys Conclusion: Deletion of miR-214 promotes interstitial inflammation in mouse models of ADPKD kidney mRNA profiles of Pkd2-KO and Pkd2-miR-214 KO were determined by polyA mRNA sequencing with an N=3 different biological replicates in each group
  • variables:
  • bulk RNA-seq,
  • genotype

1 Publications

Trail: HTExperiment

6 Samples

Trail: HTExperiment