| Experiment Id | GSE206013 | Name | Single-cell RNA-sequencing of Mettl14 conditional knock-out retinas and matched controls |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-09-11 |
| description | Post-transcriptional m6A methylation on mRNA plays a key role in neural development. Here, we specifically depleted Mettl14 (a key component of m6A complex) in retina progenitor cells by crossing Mettl14 fl/fl mice with the Chx10-Egfp/Cre mouse line and investigated cell type and transcriptome changes in the developing retinas using scRNA-seq. Retinas of Mettl14 fl/fl;Chx10-Egfp/Cre (Mettl14-cKO) mice and age matched controls were collect at P7 and applied to scRNA-seq. |
