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HT Experiment :

Experiment Id  GSE225766 Name  Spatial Transcriptiomics of Mouse Skeletal Muscle
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2023-07-07
description  Asynchronous skeletal muscle degeneration/regeneration is a hallmark feature of Duchenne muscular dystrophy (DMD); however, traditional -omics technologies that lack spatial context make it difficult to study the biological mechanisms of how asynchronous regeneration contributes to disease progression. Here, using the severely dystrophic D2-mdx mouse model, we generated a high-resolution cellular and molecular spatial atlas of dystrophic muscle by integrating spatial transcriptomics and single-cell RNAseq datasets.
  • variables:
  • genotype,
  • spatial RNA-seq

1 Publications

Trail: HTExperiment

11 Samples

Trail: HTExperiment