| Experiment Id | GSE213502 | Name | Transcriptome Ts66Yah |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-07-10 |
| description | We have created the Ts66Yah a new model for Down syndrome or T21, derived from the Ts65Dn. Ts66Yah does not contain a set of genes present in 3 copies that are not linked to T21. On this model (Ts66), we performed an RNA seq analysis on 2 structures (hippocampus and entorhinal cortex, ref: S18276) and we have done the same experiment on the Ts65Dn line to compare the 2 models. For this we sampled the hippocampus (hippo) and the entorhinal cortex (EntCortex) from 6 wild-type control male littermate animals and 6 males trisomic individual (Ts66 or Ts65). 11 individuals, 5 control and 6 Ts, 2 brain regions Hippocampus and Entorhinal cortex |
