| Experiment Id | GSE142269 | Name | Sequential regulation of glutamatergic and subtype-specific projection neuron identities in the developing cerebral cortex |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-10-18 |
| description | Purpose:To asses changes in gene expression profiles of cortices from the P0 wild type littermate controls and Tle4-/- null mutant mice. Methords:Total RNA was isolated and sequenced using an illumina high-seq 2500. Raw data was analyzed using TopHat. Genes were considered significantly changed whicn perform P value <= 0.05 Results: Compared to controls, 306 genes were significantly down-regulated in the Tle4 null mutant mice, and 338 genes were significantly up-regulated in the Tle4 null mutant mice. Cortex RNA profiles of P0 Wild type mice brain, and Tle4-/- null mutant mice brain |
