Experiment Id | GSE161395 | Name | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during root development |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-07-19 |
description | We show that Ror2 mediated non-canonical Wnt signaling in the dental mesenchyme plays a critical role in cell proliferation and thereby regulates root development size in mouse molars. Furthermore, Cdc42 acts as a potential downstream mediator of Ror2 signaling in root formation. we detected the tooth development in in Ror2 conditional knockout mouse models |