Experiment Id | GSE224780 | Name | An integrated multiorgan feed-forward metabolic response exacerbates muscle wasting and lipid accumulation in human mitochondrial myopathies |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-07-21 |
description | To investigate the systemic impact of muscle COX10 deficiency, a model of mitochondrial myopathy, we collected skeletal muscle, liver, and hypothalamus from end-stage (200d days) control and COX10 KO mice. Skeletal muscle, liver and hypothalamus were used for gene expression analyses. Libraries were sequenced with single-end 86 bps on an Illumina NextSeq500 sequencer |