| Experiment Id | GSE202297 | Name | Identification of a shared disease-associated oligodendrocyte signature among multiple CNS pathologies |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | GEO | Curation Date | 2023-08-18 |
| description | The role of oligodendrocytes in Alzheimer's disease (AD) has never been fully elucidated. To dissect their possible contribution to the disease we perform single-cell RNA-sequencing (scRNA-seq) on the brains of healthy and 5XFaD (genetic model of AD) at different ages. We performed massively parallel single-cell RNA sequencing (MARS-seq2.0) on non-immune cells (CD45-) or specifically on oligodendrocytes (GalC+) from brains of WT and 5XFaD mice. |
