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HT Experiment :

Experiment Id  GSE214392 Name  Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2023-08-25
description  We demonstrate in mice that perinatal SERT expression in glutamatergic pyramidal neurons in the hippocampus and mPFC modulates sexually dimorphic gene expression during hippocampal circuit assembly and is a source for sex-biased susceptibilities to cognitive and behavioral impairments. Comparative gene expression profiling analysis of RNA-seq data from dorsal hippocampal tissues dissected from P7 SERTPyramid and SERTfl/fl control pups in three replicates; each replicate consisted of dorsal hippocampus tissue pooled from four mice.
  • variables:
  • sex,
  • bulk RNA-seq,
  • genotype

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment