| Experiment Id | GSE214392 | Name | Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-08-25 |
| description | We demonstrate in mice that perinatal SERT expression in glutamatergic pyramidal neurons in the hippocampus and mPFC modulates sexually dimorphic gene expression during hippocampal circuit assembly and is a source for sex-biased susceptibilities to cognitive and behavioral impairments. Comparative gene expression profiling analysis of RNA-seq data from dorsal hippocampal tissues dissected from P7 SERTPyramid and SERTfl/fl control pups in three replicates; each replicate consisted of dorsal hippocampus tissue pooled from four mice. |