Experiment Id | GSE221004 | Name | Effect of smooth muscle specific PRDM6 depletion on Aorta and Ductus Arterious (DA) development |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-08-28 |
description | To investigate the function of PRDM6 in smooth muscle cells during outflow tract development, we have isolated the ascending aorta and the ductus arteriosus (DA) separately from the E18.5 Wnt1Cre;PRDM6f/f mouse (PRDM6 KO) and PRDM6f/f mouse (Control) and compared the gene expression profile of the four groups of samples There are four groups of samples in our experiment (Control Aorta; PRDM6 KO Aorta; Control DA; PRDM6 KO DA), and we focused on comparing Control DA v.s PRDM6 KO DA |