| Experiment Id | GSE231795 | Name | Altered cartilage gene expression in Aga2 OI mouse negatively impacts linear growth through Sox9 and FGF signaling |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-10-26 |
| description | Osteogenesis Imperfecta is characterized by short stature however the cellular mechanisms behind this phenotype are unclear. We isolated tibial and femoral cartilage growth plate chondrocytes from postnatal day 5 wild type and Aga2 (a model of OI) mice and analyzed differential expression patterns using single cell RNA-seq Growth plate chondrocytes from Wild-type and Aga2 mice were isolated from femoral and tibial cartilage tissue at postnatal day 5 and analyzed using scRNAseq. |
