| Experiment Id | GSE221375 | Name | Superior Expansion of Zone 2 Hepatocytes in Pregnancy |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | GEO | Curation Date | 2024-08-23 |
| description | We found that the hepatocyte proliferation wave initiated from zone 1/2 to zone 2/3 during early-to-late pregnancy, resulting in the generation of most new hepatocytes in zone 2. By single-cell RNA sequencing, we identified that Ccnd1 was highly enriched in zone 2. Mouse primary hepatocytes were isolated from 8-week-old mice by two-step collagenase perfusion, and analyzed using scRNAseq. |
