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HT Experiment :

Experiment Id  GSE77029 Series Id  E-GEOD-77029
Name  Distinct myeloid progenitor differentiation pathways uncovered through single cell RNA sequencing Experiment Type  RNA-Seq
Study Type  Baseline Source  GEO
Curation Date  2024-01-22
description  Haematopoietic stem cells can differentiate into all blood cell types. In this process, cells become progressively restricted to a single cell type. The order in which differentiating cells loose lineage potential, and the prospective isolation of cells with a defined potential remains a long-standing question. We performed gene expression analysis of haematopoietic cells from Gata1-EGFP reporter mice, leading to a model for hematopoiesis where the initial lineage decision consists of a seperation of erythroid/megakaryocyte/mast cell/eosinophil potential from lymphopoietic/monocyte/neutrophil potential Find unbiased heterogeneity in the preGM hematopoietic progenitor population
  • variables:
  • single cell RNA-seq

1 Publications

Trail: HTExperiment

64 Samples

Trail: HTExperiment