| Experiment Id | GSE221959 | Name | Single-nucleus RNA sequencing of the hippocampal formation from a genetically diverse Alzheimer's disease mouse model (AD-BXDs) |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | GEO | Curation Date | 2024-08-23 |
| description | Cognitive resilience describes a subset of the elderly population that present no cognitive decline despite harboring Alzheimer's disease (AD) neuropathologies. We used single nucleus RNA-sequencing to profile the hippocampal formation of cognitively resilient and susceptible AD-BXD strains. Hippocampal formation was isolated from cognitively resilient and cognitively susceptible AD-BXD strains (5XFAD mutation carriers) and their nontransgenic counterparts at 6- and 14-months of age. Samples were flash-frozen and were used for snRNA-sequencing. |
