Experiment Id | GSE126687 | Name | Transcriptom analysis of ZFP708 loss and overexpression in preimplantation embryos and embryonic stem cells |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2024-02-28 |
description | This work describes the function and targets of a maternal KRAB-Zinc finger protein, ZFP708, which specifically mediates maintenance of DNA-methylation at a subset of LTR retrotransposons during embryonic epigenetic reprogramming. This dataset contains RNA-seq analysis of wildtype and maternal ZFP708 knock out GV oocytes, zygotes, 2-cell stage embryos, blastocysts and embryonic stem cells derived from maternal/zygotic ZFP708 embryos. It further contains expression analysis of ZFP708 overexpressing mouse embryonic stem cells. |