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HT Experiment :

Experiment Id  GSE126687 Name  Transcriptom analysis of ZFP708 loss and overexpression in preimplantation embryos and embryonic stem cells
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2024-02-28
description  This work describes the function and targets of a maternal KRAB-Zinc finger protein, ZFP708, which specifically mediates maintenance of DNA-methylation at a subset of LTR retrotransposons during embryonic epigenetic reprogramming. This dataset contains RNA-seq analysis of wildtype and maternal ZFP708 knock out GV oocytes, zygotes, 2-cell stage embryos, blastocysts and embryonic stem cells derived from maternal/zygotic ZFP708 embryos. It further contains expression analysis of ZFP708 overexpressing mouse embryonic stem cells.
  • variables:
  • developmental stage,
  • bulk RNA-seq,
  • genotype

1 Publications

Trail: HTExperiment

61 Samples

Trail: HTExperiment