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HT Experiment :

Experiment Id  GSE226093 Name  APOE3 genotype extends lifespan in rodent models of tauopathy
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2024-08-26
description  To gain insight into the role of human APOE on tau-associated neurodegeneration, we examined P301S mutant tau transgenic mice carrying humanized APOE alleles We performed gene expression profiling of the forebrains of P301S mutant tau transgenic mice carrying humanized APOE alleles alongside mice with humanized APOE alleles. Brains from mice that reached end stage phenotype (hindlimb paralysis) were collected.
  • variables:
  • genotype,
  • bulk RNA-seq

1 Publications

Trail: HTExperiment

21 Samples

Trail: HTExperiment