Experiment Id | GSE226093 | Name | APOE3 genotype extends lifespan in rodent models of tauopathy |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2024-08-26 |
description | To gain insight into the role of human APOE on tau-associated neurodegeneration, we examined P301S mutant tau transgenic mice carrying humanized APOE alleles We performed gene expression profiling of the forebrains of P301S mutant tau transgenic mice carrying humanized APOE alleles alongside mice with humanized APOE alleles. Brains from mice that reached end stage phenotype (hindlimb paralysis) were collected. |