Experiment Id | E-MTAB-1929 | Name | Transcriptional regulation of endocrine cell differentiation by Insm1 |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | ArrayExpress | Curation Date | 2024-04-01 |
description | This experiment used RNA-Seq technology to explore gene expression in mouse Insm1^GFP/Pdx1^CFP HIGH [het/het] FACS sorted pancreatic cells (pre-beta cells) and Insm1^GFP/Pdx1^CFP LOW [het/het] cells (other endocrine progenitors) at E15.5 and E18.5. Comparison of Insm1 +/Pdx HIGH and Insm1 +/Pdx LOW cells revealed a set of differentially expressed genes that are required for beta cell specification. |