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HT Experiment :

Experiment Id  E-MTAB-11940 Name  Mapping the cellular and molecular landscape of cardiac non-myocytes in murine type-2 diabetes
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  ArrayExpress Curation Date  2024-07-26
description  Here we define key single-cell transcriptional alterations within cardiac non-myocytes, from ventricles of spontaneously type-2 diabetic (db/db) and control (db/h) mouse hearts ([B6.BKS(D)-Lepr<db>/J], stock #000697). The cell preparation sequenced consisted of metabolically active, live and nucleated non-myocyte cells, which were depleted of endothelial cells. The objective of this experiment was to develop a framework for understanding the dynamics of cardiac cell networks in murine type-2 diabetes, as a resource for future mechanistic studies.
  • variables:
  • genotype,
  • single cell RNA-seq

1 Publications

Trail: HTExperiment

2 Samples

Trail: HTExperiment